2026-10-12T11:12:00Z https://www.scidb.cn/oai

10.11922/sciencedb.o00025.00001 2022-06-06T15:29:37Z

2022-06-06 kocak-19 vaccine candidate (covid-19) doi:10.11922/sciencedb.o00025.00001 en Here we report the development of an inactivated SARS-CoV-2 vaccine candidate and show that its efficacy and safety in preclinical studies warrant further clinical evaluation. Efficiency and possible side effects of vaccine candidate on different doses were evaluated using histopathology, K18 hACE2 transgenic mice challenge, T-cell response, and serum neutralization test in Balb/c mice.  covid-19; preclinical; vaccine; mice; transgenic; ferrets engin alp onen kivilcim sonmez funda yildirim elif kervancioglu demirci aydin gurel PUBLIC https://creativecommons.org/licenses/by-nc-sa/4.0/ dataset http://www.doi.org/10.21203/rs.3.rs-1073686/v1 Science Data Bank