2026-10-15T05:01:59Z https://www.scidb.cn/oai

10.57760/sciencedb.011tj 2026-09-17T08:17:34Z

2026-09-17 Cross-platform endothelial and angiogenic marker re-analysis in pterygium: eighteen-gene statistics doi:10.57760/sciencedb.011tj en This dataset supports the companion manuscript submitted to Scientific Reports on a cross-platform endothelial and angiogenic marker re-analysis in pterygium.The primary table, EighteenGene_GSE2513_statistics.csv, provides the complete differential-expression statistics for the eighteen vascular, endothelial, hypoxia and lymphatic marker genes of the study panel in GSE2513 (pterygium n = 8 versus normal conjunctiva n = 4; GPL96 Affymetrix HG-U133A). Values are at gene level, after median aggregation of multi-probe genes, and the probe used, the Welch t statistic, the nominal P value and the Benjamini-Hochberg adjusted P value are given for every gene. It is the electronic version of Table 1 of the manuscript.The package additionally contains: (i) a 24-gene x 5-dataset directional consistency matrix (GSE2513, GSE51995, GSE208384, GSE155776, PRJNA669964), which is a wider gene set than the study panel and should not be confused with it; (ii) independent-validation panel statistics for PRJNA669964, a cohort that took no part in dataset discovery; (iii) promoter-region methylation change (delta-beta) for GSE289869; (iv) supplementary analyses comprising pathway and cell-type scores, protein-protein interaction topology, per-cohort effect-size combination, and a hypothesis-generating drug-signature screen; and (v) all analysis scripts and all main and supplementary figure files.Nine public datasets in total are re-analysed. The complete dataset list, the role of each dataset, and statements on which supplementary outputs are not relied upon in the manuscript are given in the package README. All input data are previously published, de-identified public datasets; no new experimental or human-subject data were generated, and no individual-level human data are included.Related dataset: this entry is one of two companion datasets from the same group. The other entry (https://www.scidb.cn/anonymous/aml5QWp5) analyses two of the datasets used here (GSE2513 and GSE208384) for a different question, endpoint and output; the two entries are complementary and are not duplicate publications. pterygium; endothelial activation; angiopoietin-2; VEGFA; cross-platform re-analysis; transcriptomic meta-analysis; DNA methylation; bioinformatics Lin Zhu PUBLIC https://creativecommons.org/licenses/by/4.0/ dataset Science Data Bank