2026-10-14T18:19:26Z https://www.scidb.cn/oai

10.57760/sciencedb.0131a 2026-10-08T11:10:33Z

2026-10-08 Synthetic MSK-IMPACT 2017 cohort: audited clinical-variant tables and simulated FASTQ reads from a hybrid generative pipeline doi:10.57760/sciencedb.0131a en This version contains 10,328 synthetic clinical–variant records and 2,000 simulated single-end FASTQ files. A stable record index and an audited mapping link selected table rows to FASTQ archive members. The release also provides classified simulator-input specifications, quality flags, corrected validation data, an independent full-archive integrity audit, and a bounded 21-mer recount from publicly downloadable reads. The clinical fields and variant lists were generated separately; not every named alteration is represented by an alteration-specific or observed read-level event. The dataset supports record-to-file retrieval and controlled workflow testing, but is not a clinical cohort, an all-variant calling truth set, or a formal privacy guarantee. synthetic data; NGS simulation; cancer genomics; MSK-IMPACT; generative models; FASTQ benchmarking; record-to-file linkage Yanlong Li Zhangyi Shen PUBLIC https://opendatacommons.org/licenses/odbl/1-0/ dataset Science Data Bank