2026-10-11T01:37:12Z https://www.scidb.cn/oai

10.57760/sciencedb.01823 2022-06-06T15:16:17Z

2022-06-06 Code for Supplementary Figure 7 of 'De novo variants in genes regulating stress granule assembly associate with neurodevelopmental disorders' doi:10.57760/sciencedb.01823 en Model comparison and gene constrain analysis. a, Venndiagrams show gene overlap between CH model and DenovolyzeR model in terms of LGDmutations and missense mutations, respectively. b, Comparison of gnomAD pLI score andMis Z score of known SG-related NDD genes (KNOWN, gnomAD pLI: n = 17; Mis Zscore: n = 20), newly implicated SG-related NDD genes (NEW, gnomAD pLI: n = 22; MisZ score: n = 38). and SG genes without significant NDD association (FALSE, gnomADpLI: n = 800; Mis Z score: n = 785) (two-tailed Wilcoxon rank sum test) autism; Neurodevelopmental disorder; Candidate genes Tan Senwei Hui Guo PUBLIC https://creativecommons.org/licenses/by-nc-nd/4.0/ dataset http://www.doi.org/10.1126/sciadv.abo7112 Science Data Bank