2026-10-14T20:19:42Z https://www.scidb.cn/oai

10.57760/sciencedb.03353 2022-10-12T14:01:14Z

2022-10-12 chip-seq data of C57 mouse spleen derived CD8+ T cells lactate/lithium carbonate treated with lactylated doi:10.57760/sciencedb.03353 en The data used CD8+T cells from C57 mouse spleen. After being activated by CD3/28, they were treated with 10mM lactic acid and 1mM lithium carbonate for 24 hours respectively. The cells were fixed, and protein and gene location information were stabilized after cross-linking. Chip seq was used to analyze the histone gene sites modified by pan Kla. They are divided into the following four groups:; 1. The control group (CTR) was solvent control; 2. The lactic acid treatment group (10LA) was treated with 10mM lactic acid for 24 hours; 3. The lithium carbonate treatment group (LA) was treated with 1mM lithium carbonate for 24 hours; 4. The lactic acid/lithium carbonate group (10LALC) was treated with 10mM lactic acid and 1mM lithium carbonate for 24 hours.  CD8+T; Lactylation; chip-seq; lithium carbonate 唐亮 黄波 JING WEI MA YAO YAO TAN PUBLIC https://creativecommons.org/licenses/by/4.0/ dataset http://www.doi.org/10.1038/s41590-023-01738-0 Science Data Bank