2026-10-11T21:21:38Z https://www.scidb.cn/oai

10.57760/sciencedb.05804 2022-10-31T16:29:53Z

2022-10-31 Discovery of a highly potent kinase inhibitor capable of overcoming multiple imatinib-resistant ABL mutants for chronic myeloid leukemia (CML) doi:10.57760/sciencedb.05804 en ABL mutations inhibitory activity in BAF3 cellsModels of ABL kinase wt and mutantsAntiproliferation of CHMFL-48 in CML cell lines In vivo anti-tumour efficacy  BCR-ABL; ABL mutants; Chronic myeloid leukemia; Kinase inhibitor; Imatinib resistance Tingting Lu Jiangyan Cao Fengming Zou Xixiang Li Aoli Wang Wenliang Wang Huamin Liang Qingwang Liu Chen Hu Cheng Chen Zhenquan Hu Wenchao Wang Lili Li Jian Ge Yang Shen Tao Ren Jing Liu Ruixiang Xia Qingsong Liu PUBLIC https://creativecommons.org/licenses/by-nc/4.0/ dataset http://www.doi.org/https://doi.org/10.1016/j.ejphar.2021.173944 Science Data Bank