2026-10-13T02:39:02Z https://www.scidb.cn/oai

10.57760/sciencedb.05840 2022-11-02T17:13:28Z

2022-11-02 Discovery of (E)-N-(4-methyl-5-(3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thiazol-2-yl)-2-(4-methylpiperazin-1-yl)acetamide (IHMT-TRK-284) as a novel orally available type II TRK kinase doi:10.57760/sciencedb.05840 en IC50, GI50，signaling pathway，NMR, LC-MS, in vivo efficacy IC50; GI50; Signaling pathway; NMR; LC-MS; in vivo efficacy Beilei Wang Wentao Zhang Xuesong Liu Fengming Zou Junjie Wang Qingwang Liu Aoli Wang Zhenquan Hu Yongfei Chen Shuang Qi Zongru Jiang Cheng Chen Chen Hu Li Wang Jing Liu Wenchao Wang Qingsong Liu PUBLIC https://creativecommons.org/licenses/by-nc/4.0/ dataset http://www.doi.org/10.1016/j.ejmech.2020.112744 Science Data Bank