2026-10-14T21:58:29Z https://www.scidb.cn/oai

10.57760/sciencedb.11721 2023-09-27T14:03:11Z

2023-09-27 A newly isolated intestinal bacterium involved in C-ring cleavage of flavan-3-ol monomers and antioxidant activity of the metabolites doi:10.57760/sciencedb.11721 en We isolated a strain from porcine cecum content, which is capable of cleaving the heterocyclic C-ring to form 1-(3',4'-dihydroxyphenyl)-3-(2'',4'',6''-trihydroxyphenyl)propan-2-ol from (+)-catechin and (-)-epicatechin, and 1-(3',4',5'-trihydroxyphenyl)-3-(2'',4'',6''-trihydroxyphenyl) propan-2-ol from (-)-epigallocatechin. The strain was identified as Streptococcus pasteurianus (Streptococcus gallolyticu subsp. Pasteurianus, designated as F32-1) based on 16S rDNA similarity and MALDI-TOF-MS identification. The formation of the C-ring cleavage structural unit by the F32-1 strain enhanced the chemical antioxidant ability and altered the cellular antioxidant activity of (+)-catechin, (-)-epicatechin and (-)-epigallocatechin. The dataset includes screening result, metabolites identification data, and antioxidant activity data Streptococcus pasteurianus; C-ring cleavage metabolites; antioxidant activity Ruonan Liu PUBLIC https://creativecommons.org/publicdomain/zero/1.0/ dataset http://www.doi.org/10.1039/d3fo03601d Science Data Bank