2026-10-12T09:43:18Z https://www.scidb.cn/oai

10.57760/sciencedb.14072 2023-12-08T09:53:42Z

2023-12-08 Automated and remote synthesis of poly(ethylene glycol)-mineralized ZIF-8 composite particles via a synthesizer assisted by femtosecond laser micromachining doi:10.57760/sciencedb.14072 en Mineralization of the ZIF-8 in the presence of biomacromolecules has been demonstrated to be a general way for making bioentities@ZIFs composites. The ZIF-8 crystals permit controlled storage and utilization of the bioentities, thus can benefit drug delivery, cold-chain breaking etc. With the increasing needs on personal care and distributed manufacturing, automated synthesis controlled by a computer becomes the next challenge. In this work, we designed an automatic synthesis system to prepare PEG mineralized ZIF-8 composite particles. This system is based on flow chemistry with the microfluidic chips fabricated by femtosecond laser micromachining. The particles were synthesized and monitored automatically. Furthermore, this synthesizer could be extended for fabrication of vaccine particles under remote control through internet. ZIF-8; Automatic synthesis; Remote synthesis Miao Wu Lingling Xia Yucen Li Difeng Yin Jianping Yu Wenbo Li Ning Wang Xin Li Jiwei Cui Wei Chu Ya Cheng Ming Hu PUBLIC https://creativecommons.org/licenses/by-nc-nd/4.0/ dataset Science Data Bank