2026-10-14T12:45:12Z https://www.scidb.cn/oai

10.57760/sciencedb.16694 2024-11-15T18:51:14Z

2024-11-15 Measurement of 232Th(p, x)225Ac reaction cross-section at CSNS APEP facility up to 80 MeV doi:10.57760/sciencedb.16694 en The data related to the article "Measurement of 232Th(p, x)225Ac reaction cross-section at CSNS APEP facility up to 80 MeV" submitted to the journal of Nuclear Science and Techniques. The radioisotope actinium-225 (225Ac) has been successfully used in Targeted Alpha Therapy (TAT) in pre-clinical and clinical due to its excellent nuclear characteristics. Medium- and high-energy proton spallation reactions on thorium are the most significant methods for producing 225Ac. This work aims to examining the possibility of producing 225Ac by irradiation of thorium oxide with medium-energy protons. Thorium oxide sheets were irradiated with 40-, 50-, 60-, 70-, 80-MeV protons at the Associated Proton beam Experiment Platform (APEP) of China Spallation Neutron Source (CSNS). The cross-sections for formation of 225Ac have been measured using the activation method and off-line gamma-ray spectrometric technique. The experimental results were compared with the existing data from EXFOR, as well as the theoretical data from TENDL. Based on the experimental cross section and theoretical calculation, the production yield of 225Ac in the irradiated thorium targets was examined. The results show that APEP is capable of producing sufficient quantities of 225Ac for purification and clinical therapy. This work is the first measurement of proton-induced nuclear reaction cross sections at CSNS APEP. The data file is uploaded in table format, with specific descriptions as follows：Data.xlsx: Comparison of the present experimental data, several existing data from EXFOR, and the evaluated data from TENDL-2021. 232Th target; Proton irradiation; 225Ac producing cross section; CSNS APEP Bing Jiang Binbin Tian Hantao Jing Qifan Dong Lu Guo PUBLIC https://creativecommons.org/licenses/by/4.0/ dataset http://www.doi.org/https://doi.org/10.1007/s41365-024-01616-w Science Data Bank