2026-10-14T05:24:41Z https://www.scidb.cn/oai

10.57760/sciencedb.21004 2025-02-18T17:17:47Z

2025-02-18 Neocryptolepine Derivatives Anti-tumor Database System (NDADS) doi:10.57760/sciencedb.21004 en Neocryptolepine is a natural alkaloid isolated from the African climber C. sanguinolenta, belonging to the indoloquinoline group of alkaloids. This compound has become a natural source pioneer widely studied by medicinal chemists due to its diverse biological activities, especially its potential applications in antitumor, anti-inflammatory, and antimalarial fields. As a natural product with diverse bioactivities, neocryptophylline has great potential for ovarian cancer therapeutic studies. Through in-depth research and development of Neocryptophylline, it may provide new therapeutic options for ovarian cancer patients in the future. Ovarian cancer is a malignant tumor that poses a serious threat to women's health, and the field of its treatment and research has been progressing. In the treatment of ovarian cancer, targeted therapy and immunotherapy have become important research directions, especially drug development for specific targets. Drug development and clinical application of targets provide more treatment options for ovarian cancer patients and are expected to improve the survival rate and quality of life of patients. With the deepening of scientific research, more new targets may be discovered in the future, bringing new breakthroughs in the treatment of ovarian cancer. Using bioinformatics tools and statistical methods to analyze large-scale datasets to identify biomarkers of therapeutic response and potential new targets is also a key research direction. Studying ovarian cancer targets can help identify new biomarkers that can be used for early diagnosis, efficacy monitoring and prognostic assessment of the disease. For example, the expression level of certain proteins or genes may be closely related to the severity of the disease or the response to treatment. In conclusion, research on ovarian cancer targets is not only of great significance for scientific development, but also has a profound impact on improving patient outcomes and quality of life and promoting medical progress. In order to integrate and evaluate numerous research resources and results, literature and information extraction and analysis of Neocryptolepine and ovarian cancer were carried out, so as to construct the inhibitory activities of Neocryptolepine targets and compounds on various types of cancers as well as the relevance of targets on ovarian cancer, in order to assist in the discovery of ovarian cancer targets for the treatment of related diseases, and to supplement the current inclusion situation, covering various types of The interface supports the above new Hakuhodo compounds' names, structures, molecular weights, activities, functions, cancer types, cancer cells, targets/signaling pathways, references, and corresponding URL sources. The interface supports the query function of the above content of neo-Leucovorin. Therefore, this antitumor database of Neocryptolepine Derivatives will be helpful to study the possibility of Neocryptolepine as a target in the treatment of ovarian cancer from multiple aspects of activity, structure, method of action, and target, which will help in the treatment of ovarian cancer and improve the survival rate of ovarian cancer. ovarian cancer; database; neocryptolepine Chen Peng 张华 PUBLIC https://creativecommons.org/publicdomain/zero/1.0/ dataset Science Data Bank