2026-10-11T01:14:56Z https://www.scidb.cn/oai

10.57760/sciencedb.24274 2025-04-27T16:19:13Z

2025-04-27 differentially expressed genes (DEGs) in cartilage tissues of normal and KOA rats. doi:10.57760/sciencedb.24274 en In our study, we first employed RNA-sequencing to analyze differentially expressed genes in cartilage tissues of normal and KOA rats. We identified TNN, the gene encoding tenascin-N protein (also known as tenascin-W) , which was significantly differentially up-regulated in the KOA group. To further analyze the downstream target genes of TNN, we performed RNA-sequencing on IL-1β-stimulated KOA chondrocytes (KOA group) and KOA chondrocytes treated with TNN (KOA+TNN group). knee osteoarthritis; tenascin-W; cartilage damage Chenhao Wang You Wulin PUBLIC https://creativecommons.org/licenses/by-nc/4.0/ dataset Science Data Bank