2026-10-14T13:22:40Z https://www.scidb.cn/oai

10.57760/sciencedb.27252 2025-06-30T10:12:51Z

2025-06-30 IN VITRO RAW DATA OF SILVER NANOPARTICLES FROM Ficus deltoidea EXTRACT (FD-AGNPS) AS ANTI-CERVICAL CANCER AGENT doi:10.57760/sciencedb.27252 en This study investigates the potential of green-synthesized silver nanoparticles using Ficus deltoidea leaf extract (FD-AgNPs) as a novel anti-cervical cancer agent. Cervical cancer progression is closely linked to dysregulated apoptosis and epithelial-mesenchymal transition (EMT), both of which contribute to tumor growth and metastasis. FD-AgNPs, synthesized through a plant-based eco-friendly approach, demonstrated significant pro-apoptotic activity and EMT inhibition in HeLa cervical cancer cells. The bioactive phytochemicals in Ficus deltoidea serve as natural reducing and capping agents, enhancing the biocompatibility and therapeutic potential of the nanoparticles. This dual mechanism, inducing cancer cell death and reducing metastatic behavior, highlights FD-AgNPs as a promising candidate for the development of safe, effective, and sustainable nanomedicine-based therapies against cervical cancer. cervical cancer; apoptosis; metastasis; silver nanoparticles; Ficus deltoidea Happy Kurnia Permatasari Raisha Anis Fatiha Christian Kencana Ngabdi Jihan Salwa Azizah Bayu Lestari To Soon Wei Nik Ahmad Nizam Nik Malek PUBLIC https://creativecommons.org/licenses/by/4.0/ dataset Science Data Bank