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    <identifier>10.57760/sciencedb.27301</identifier>
    <datestamp>2025-07-02T13:57:35Z</datestamp>
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  <dc:date>2025-07-02</dc:date>
  <dc:title>CypA promotes PDCoV replication by inhibiting ubiquitin&amp;ndash;dependent degradation of viral spike protein</dc:title>
  <dc:identifier>doi:10.57760/sciencedb.27301</dc:identifier>
  <dc:language>en</dc:language>
  <dc:description>	CypA 是一种宿主蛋白，在病毒感染中起重要作用并调节病毒复制。本研究发现 CypA 可以显着促进宿主细胞中 PDCoV 的复制。并且它可以与 PDCoV S 蛋白相互作用，参与维持 S 蛋白的稳定性，以防止其蛋白酶体途径降解，从而促进 PDCoV 复制。本研究的结果为进一步理解 PDCoV-宿主相互作用的机制提供了新的见解。</dc:description>
  <dc:subject>PDCoV; CypA; spike protein; viral replication; ubiquitination</dc:subject>
  <dc:creator>peng yousheng</dc:creator>
  <dc:rights>PUBLIC</dc:rights>
  <dc:rights>https://creativecommons.org/publicdomain/zero/1.0/</dc:rights>
  <dc:type>dataset</dc:type>
  <dc:publisher>Science Data Bank</dc:publisher>
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