2026-10-12T03:12:20Z https://www.scidb.cn/oai

10.57760/sciencedb.28802 2025-09-26T14:39:58Z

2025-09-26 Transcriptomic and Untargeted Metabolomic Responses of Candida glabrata to Lactate Condition doi:10.57760/sciencedb.28802 en Infections caused by the Candida genus, including Candida glabrata, pose significant clinical challenges due to their ability to colonize diverse host niches, where metabolic interactions between the pathogen and host play a pivotal role in disease progression. As central metabolites in human physiology, lactate and its salts serve not only as energy sources but also as key environmental metabolites at infection sites (e.g., the vagina) and as critical signaling molecules regulating microbial virulence. By comparing the transcriptional and metabolic profiles of C. glabrata in response to lactate, this study investigates the impact of lactate on C. glabrata. Candida glabrata; Metabolomics; Transcriptomics Geng Lv Si-Jia Huang Jun-Tao Zhao Jin-Yan Liu Lu-Ling Wang Ming-Jie Xiang PUBLIC https://creativecommons.org/licenses/by-nc-sa/4.0/ dataset Science Data Bank