2026-10-13T19:25:19Z https://www.scidb.cn/oai

10.57760/sciencedb.28872 2025-08-08T10:08:29Z

2025-08-08 Effectiveness of non-invasive brain stimulation for Children With Attention Deficit Hyperactivity Disorder: A Meta-Analysis of Randomized Controlled Trials doi:10.57760/sciencedb.28872 en Objective: To evaluate the effectiveness of non-invasive brain stimulation on core symptoms and executive function in children with Attention Deficit Hyperactivity Disorder (ADHD). Methods: A search was conducted in CNKI, Wanfang, VIP, SinoMed, PubMed, Web of Science, Embase and Cochrane Library for RCTs on non-invasive brain stimulation for children with ADHD from database inception to 7 March 2025. The control group received sham stimulation or conventional rehabilitation, while the observation group received non-invasive brain stimulation techniques. Risk of bias was assessed using the Cochrane Handbook for Systematic Reviews, and meta-analysis was performed using RevMan 5.4. Results: Twelve studies were included, covering 336 patients and 3 interventions: rTMS, tDCS and tRNS. Meta-analysis showed non-invasive brain stimulation could significantly lower hyperactivity/impulsivity scores (SMD=-1.20, 95%CI: -1.81~-0.59, P<0.05), and increase nogo trial accuracy and N-back test accuracy. Subgroup analysis found rTMS and ≥4 weeks was effective for attention deficits. Conclusion: Non-invasive brain stimulation can effectively improve hyperactivity, impulsivity, response inhibition and working memory in children with ADHD. The improvement of attention deficits is influenced by treatment methods and treatment duration. Attention Deficit Hyperactivity Disorder; Non-invasive brain stimulation; Meta-analysis; child Wang Hui Du Chunyan Cai Qiuhan Yang Jia Liu Xuan RESTRICTED dataset Science Data Bank