2026-10-14T12:45:33Z https://www.scidb.cn/oai

10.57760/sciencedb.29357 2025-10-09T09:27:10Z

2025-10-09 Peptide OM-LV20 Demonstrates Neuroprotective Effects by Attenuating Mitochondrial-Mediated Neuronal Apoptosis in Traumatic Brain Injury (TBI) Mice doi:10.57760/sciencedb.29357 en Traumatic Brain Injury (TBI) is a major global health concern, especially in people under 45, causing long-term motor and cognitive impairments with limited effective therapies. Peptide OM-LV20, from odorous frogs in Southwest China, shows neuroprotection in oxidative stress, spinal cord injury, and cerebral ischemia/reperfusion. This dataset uses RNA-seq to capture transcriptomic changes in TBI mice’s frontal cortex and hippocampus after OM-LV20 intervention. It supports studying OM-LV20’s neuroprotective mechanism via mitochondria-mediated neuronal apoptosis and serves as a reusable transcriptomic resource for TBI research and drug screening. OM-LV20; Traumatic Brain Injury; mitochondrial-mediated apoptosis Chen-Jun Ye Li-Na Liu Min-Nan Lu Tao Hu Ying Zhou Dan Wang Hao-Ran Zhao Guo-Ji Yan Xin-Ying Shi Jing-Feng Song Shan-Shan Li Sai-Ge Yin Shi-Tong Zong Xin-Wang Yang Yan-Bin Xiyang RESTRICTED dataset Science Data Bank