2026-10-11T21:08:42Z https://www.scidb.cn/oai

10.57760/sciencedb.29586 2026-07-06T22:14:55Z

2026-07-06 Raw data for the article “The c-di-GMP-dependent transcriptional regulator Sfa4 controls H4-T6SS expression and virulence in Pseudomonas aeruginosa” doi:10.57760/sciencedb.29586 en This dataset contains the raw experimental data related to Sfa4-mediated regulation of H4-T6SS and virulence in the clinical Pseudomonas aeruginosa strain LYSZa7, including:Transcriptional level data of T6SS-related genes (tssB4, tssH4, amrZ, fleQ, etc.) detected by RT-qPCR;Original bands and gray-scale quantitative data of TssB4 protein expression detected by Western blot;Raw results and statistical analysis data from antibacterial competition assays, biofilm formation assays, A549 cell cytotoxicity assays, and Galleria mellonella infection assays;Raw RNA-seq data (deposited in NCBI BioProject under accession number PRJNA1372908).All data are the supporting raw data for the paper “The c-di-GMP-dependent transcriptional regulator Sfa4 controls H4-T6SS expression and virulence in Pseudomonas aeruginosa” and can be used for result verification and subsequent research reuse. Clinical Pseudomonas aeruginosa; T6SS diversity; c-di-GMP signaling; Transcriptional regulator; Microbial competition; Biofilm regulation Yizhou Zhang Tian Ye Jie Deng Zhao Cai Yingdan Zhang Yuanyuan Ma Peng Xue Yang Liu Jiuxin Qu Tian Zhou PUBLIC https://creativecommons.org/licenses/by/4.0/ dataset Science Data Bank