2026-10-12T06:19:18Z https://www.scidb.cn/oai

10.57760/sciencedb.30139 2025-11-14T18:24:16Z

2025-11-14 Integration of ATAC-seq and RNA-seq analysis identifies host genes related with PRRSV infection doi:10.57760/sciencedb.30139 en This integrated multi-omics study reveals that PRRSV infection remodels the host epigenome, driving changes in gene expression through altered chromatin accessibility. We identified key candidate genes (e.g., IL1B, CCL20, CSF3) and enriched immune pathways central to the viral infection mechanism. These findings provide crucial insights into PRRSV pathogenesis and unveil potential targets for novel therapeutic and vaccine strategies. ATAC-seq ; RNA-seq ; PRRSV; PAM; host genes Ao Zhou PUBLIC https://creativecommons.org/licenses/by/4.0/ dataset Science Data Bank