2026-10-12T02:32:42Z https://www.scidb.cn/oai

10.57760/sciencedb.31609 2025-11-24T17:45:16Z

2025-11-24 Characterization of Drug Resistance Mutations in People Living with HIV with Low-Level Viremia on Antiretroviral Therapy in Chongqing, China doi:10.57760/sciencedb.31609 en This dataset originates from a cross-sectional study conducted in Chongqing, China, which aimed to investigate the prevalence, mutational patterns, and associated risk factors of drug resistance mutations (DRMs) in HIV-1 infected individuals experiencing low-level viremia (LLV; viral load 50-999 copies/mL) while on antiretroviral therapy (ART).The dataset comprises epidemiological, clinical, and viral gene sequence data from 210 LLV patients identified from a screened cohort of 4,941 ART-treated individuals. A combined genotypic strategy utilizing both plasma viral RNA and proviral DNA was successfully applied to 133 (63.33%) of these LLV patients. This approach enabled the amplification and sequencing of the HIV-1 protease, reverse transcriptase, and integrase gene regions. HIV-1 subtyping and DRM analysis were performed using the Stanford HIVdb algorithm and phylogenetic analysis methods. HIV; drug resistance; low level viremia Huizheng Zhang Zhang Zhen Ye Wei Pan Weidong PUBLIC https://api.github.com/licenses/cc0-1.0 dataset Science Data Bank