2026-10-15T05:00:54Z https://www.scidb.cn/oai

10.57760/sciencedb.31733 2026-04-03T07:55:27Z

2026-04-03 Integrating single-cell Mendelian Randomization, bulk RNA sequencing, and single-cell RNA sequencing data to explore the role of chemokines in Alzheimer's disease doi:10.57760/sciencedb.31733 en Following the MR, sensitivity, and Steiger test analyses conducted between eQTL-cell pairs and AD, 2,401 eQTL-cell pairs were identified as being associated with AD using the IVW method (Supplementary File 1). Similarly, using the same analytical methods, a total of seven chemokines were identified as having causal associations with AD (Supplementary File 2), followed by 2,149 eQTL-cell pairs with causal relationships to seven chemokines (Supplementary File 3). Based on the integration of these analytical results, 2,149 key eQTL-cell pairs and seven key chemokines were identified. Alzheimer's disease; Chemokines; Biomarkers; Single-cell Mendelian Randomization; single-cell RNA sequencing Tang Min PUBLIC https://creativecommons.org/licenses/by-nc-nd/4.0/ dataset Science Data Bank