2026-10-14T04:28:03Z https://www.scidb.cn/oai

10.57760/sciencedb.32215 2026-04-03T14:14:09Z

2026-04-03 Multi-omics study of serum markers related to Alzheimer's disease doi:10.57760/sciencedb.32215 en Multi-omics and IHC analysis of 5XFAD mice identified key proteins (KATNB1, HTRA2, XRN2, UPF2) highly correlated with brain metabolites. Notably, significant differential expression of xanthines in serum suggests that xanthine could serve as a promising early biomarker for Alzheimer’s disease. Alzheimer's disease; 5XFAD genotype mice; Multi-omics; Xanthines Jianhui Yan PUBLIC dataset Science Data Bank