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    <responseDate>2026-10-14T20:36:40Z</responseDate>
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    <identifier>10.57760/sciencedb.32400</identifier>
    <datestamp>2025-11-28T10:18:20Z</datestamp>
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  <dc:date>2025-11-28</dc:date>
  <dc:title>Multi-Omics Integration Reveals SERPINB1 Epigenetic Silencing as a Key Mediator of Immunosuppressive Microenvironment and Metastasis in Prostate Cancer</dc:title>
  <dc:identifier>doi:10.57760/sciencedb.32400</dc:identifier>
  <dc:language>en</dc:language>
  <dc:description>This dataset contains the processed multi-omics data supporting the findings of the study &amp;quot;Multi-Omics Integration Reveals SERPINB1 Epigenetic Silencing as a Key Mediator of Immunosuppressive Microenvironment and Metastasis in Prostate Cancer&amp;quot;. It includes the data necessary to reproduce the figures and statistical analyses, focusing on SERPINB1 promoter hypermethylation and its role in driving an immunosuppressive tumor microenvironment and metastasis in prostate cancer. The companion code for analysis is available in the GitHub repository: https://github.com/bjshineboy/multi-omics-prostate-cancer-SERPINB1.git.</dc:description>
  <dc:subject>SERPINB1; DNA Methylation; Prostate Cancer; Tumor Microenvironment; Neutrophil Elastase; Multi-omics.</dc:subject>
  <dc:creator>He Yi</dc:creator>
  <dc:creator>Wenhua Xie</dc:creator>
  <dc:creator>Shengjie Dai</dc:creator>
  <dc:creator>zhenxuan fang</dc:creator>
  <dc:rights>PUBLIC</dc:rights>
  <dc:rights>https://mit-license.org</dc:rights>
  <dc:type>dataset</dc:type>
  <dc:publisher>Science Data Bank</dc:publisher>
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