2026-10-12T14:36:10Z https://www.scidb.cn/oai

10.57760/sciencedb.34774 2026-01-04T10:26:53Z

2026-01-04 Oral Bioavailability and Drug-Likeness Profiling of Gypenoside Derivatives Isolated from Gynostemma pentaphyllum doi:10.57760/sciencedb.34774 en Gynostemma pentaphyllum (Jiaogulan) is a traditional herbal resource rich in gypenosides, a class of triterpenoid saponins with potential pharmacological activities. This dataset presents quantitative evaluations of 10 gypenoside compounds, reporting their oral bioavailability (OB, %) and drug-likeness (DL) scores—two critical metrics for preclinical drug candidate screening. The parameters summarized herein offer foundational data to assess the translational potential of these natural saponins for pharmaceutical development, facilitating subsequent structure-activity relationship (SAR) analyses and lead compound optimization. Gypenosides; Oral Bioavailability (OB); Drug-Likeness (DL); Natural Active Compounds Li Jiayi PUBLIC https://creativecommons.org/licenses/by-nc-nd/4.0/ dataset Science Data Bank