2026-10-13T03:53:54Z https://www.scidb.cn/oai

10.57760/sciencedb.35603 2026-01-21T17:00:39Z

2026-01-21 RNA-seq profiling of host immune responses in BALB/c mice following immunization with HSV-1 ΔICP34.5ΔICP47 N doi:10.57760/sciencedb.35603 en This dataset contains RNA sequencing (RNA-seq) data generated from spleen tissues of BALB/c mice following immunization with an attenuated herpes simplex virus type 1 (HSV-1 ΔICP34.5ΔICP47 N).BALB/c mice were immunized twice with HSV-1 ΔICP34.5ΔICP47 N at a two-week interval, while control mice received phosphate-buffered saline (PBS). Spleens were collected for total RNA extraction and RNA-seq library preparation.The prepared libraries were sequenced on an Illumina platform by Chi Biotech (Shenzhen, China). This dataset enables analysis of host transcriptional and immune-related gene expression changes induced by HSV-1–based immunization. RNA seq; HSV-1 ΔICP34.5ΔICP47-N; viral immunization; immune response Caijun Sun ZIYU WEN Haohang Wang Yu Liao PUBLIC https://creativecommons.org/licenses/by/4.0/ dataset http://www.doi.org/10.1016/j.virs.2026.01.002 Science Data Bank