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    <identifier>10.57760/sciencedb.35726</identifier>
    <datestamp>2026-05-07T09:59:46Z</datestamp>
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  <dc:date>2026-05-07</dc:date>
  <dc:title>Gut microbiota profiling of patients with IgA nephropathy before and after Yishen Huashi granule treatment using 16s rRNA gene sequencing</dc:title>
  <dc:identifier>doi:10.57760/sciencedb.35726</dc:identifier>
  <dc:language>en</dc:language>
  <dc:description>This dataset contains fecal 16S rRNA gene sequencing data from patients with IgA nephropathy who received Yishen Huashi granule treatment. Fecal samples were collected before and after treatment to characterize longitudinal changes in the gut microbiota. The dataset was generated to investigate whether Yishen Huashi granules modulate intestinal microbial composition in IgA nephropathy and to explore microbiota features associated with clinical treatment response. Taxonomic profiling and downstream microbial community analyses were performed to compare gut microbiota structure, differential bacterial taxa, and response-related microbial signatures.</dc:description>
  <dc:subject>IgA nephropathy; gut microbiota; 16S rRNA sequencing; Yishen Huashi granule; traditional Chinese medicine; clinical response</dc:subject>
  <dc:creator>Tang Jingyi</dc:creator>
  <dc:rights>EMBARGO</dc:rights>
  <dc:rights>https://creativecommons.org/licenses/by-nc-nd/4.0/</dc:rights>
  <dc:type>dataset</dc:type>
  <dc:publisher>Science Data Bank</dc:publisher>
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