2026-10-14T16:48:49Z https://www.scidb.cn/oai

10.57760/sciencedb.36132 2026-01-23T18:38:02Z

2026-01-23 Necroptotic Gingival Fibroblasts Exacerbate NETs Formation in Periodontitis doi:10.57760/sciencedb.36132 en Periodontitis involves dysregulated stromal-immune interactions that exacerbate tissue damage. Although necroptosis of gingival fibroblasts (GFs) contributes to pathogenesis, the specific cellular crosstalk mechanisms remain unclear. Here, we revealed that aberrant communication between necroptotic GFs and neutrophil extracellular traps (NETs) aggravates periodontal inflammation and bone loss. periodontitis; necroptosis; NETs Chen Zehao Fuchun Fang RESTRICTED dataset Science Data Bank