2026-10-14T00:10:14Z https://www.scidb.cn/oai

10.57760/sciencedb.36253 2026-09-07T10:20:30Z

2026-09-07 Scoparone ameliorates metabolic dysfunction-associated fatty liver disease in mice by inhibiting ferroptosis through activation of the Nrf2/GPX4 pathway doi:10.57760/sciencedb.36253 en This dataset is derived from animal and cell experiments on the improvement of metabolic dysfunction-associated fatty liver disease in mice via the inhibition of ferroptosis through the activation of the Nrf2/GPX4 pathway by scoparone. It systematically records the raw data and processed results of the entire experimental process, providing data support for the conclusions of this study.The dataset contains a total of 10 files, which correspond to the graphical data of 10 figures in the paper as follows: Fig. 1: Liver photographs, HE staining and Oil Red O staining images of hepatic tissues; Fig. 2: Dynamic changes in body weight and food intake of mice; Fig. 3: Serum and hepatic related parameters of mice; Fig. 4: Mitochondrial function parameters of mouse liver; Fig. 5: PCR and Western blot (WB) analysis results of mouse liver-related indicators; Fig. 6: Concentration screening results of SCO and NaOA in cell experiments; Fig. 7: Oil Red O staining images of cells; Fig. 8: Cell-related functional parameters; Fig. 9: ROS staining images, JC-1 staining images and their corresponding fluorescence quantification results of cells; Fig. 10: PCR and Western blot (WB) analysis results of cell-related indicators. scoparone; Nrf2; GPX4; metabolic dysfunction-associated steatotic liver disease; ferroptosis Kefeng Zhang Kai Guo Houkang Cao Ya Gao RESTRICTED dataset Science Data Bank