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    <responseDate>2026-10-14T10:43:03Z</responseDate>
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    <identifier>10.57760/sciencedb.38717</identifier>
    <datestamp>2026-06-08T09:07:01Z</datestamp>
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  <dc:date>2026-06-08</dc:date>
  <dc:title>Cross-Species Comparison of iPSC-Derived Neural Stem Cells Reveals Conserved Features in Human and Dog</dc:title>
  <dc:identifier>doi:10.57760/sciencedb.38717</dc:identifier>
  <dc:language>en</dc:language>
  <dc:description>We generated and validated canine-induced pluripotent stem cells (iPSCs) derived from dermal fibroblasts. Subsequently, canine iPSCs, human iPSCs, and mouse embryonic stem cells were differentiated into neural stem cells (NSCs). In parallel, primary NSCs were isolated from canine and mouse fetal brain tissue for comparison. All NSC populations expressed canonical markers including PAX6, FOXG1, and SOX2.</dc:description>
  <dc:subject>Canine; Induced pluripotent stem cells; Neural differentiation; Cross-species comparison</dc:subject>
  <dc:creator>Xue-zhen Huang</dc:creator>
  <dc:creator>Shu-run Zhang</dc:creator>
  <dc:rights>EMBARGO</dc:rights>
  <dc:rights>https://creativecommons.org/licenses/by-nc-nd/4.0/</dc:rights>
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  <dc:publisher>Science Data Bank</dc:publisher>
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