2026-10-12T13:49:50Z https://www.scidb.cn/oai

10.57760/sciencedb.39445 2026-06-23T19:34:50Z

2026-06-23 VEGF and HIF as potential biomarkers for effective IRE in the ablation of Invasive Breast-Ductal Carcinoma doi:10.57760/sciencedb.39445 en we investigated the potential of VEGF and HIF-1α as biomarkers of response to IRE in invasive ductal breast carcinoma using a chemically induced Vietnamese swine model that closely mimics human breast tissue and tumor microenvironment. Neoplastic tissue displayed marked overexpression of HIF-1α, VEGF, and carcinoembryonic antigen (CEA) compared with healthy controls. One week after IRE treatment, a consistent reduction in all three markers was observed, indicating effective tumor ablation accompanied by suppression of hypoxia driven and proangiogenic signaling.  vegf ; hif-1; electroporation Claudia Elizabeth Vera Tizatl PUBLIC https://creativecommons.org/licenses/by-nc/4.0/ dataset Science Data Bank