2026-10-12T23:10:48Z https://www.scidb.cn/oai

10.57760/sciencedb.40939 2026-09-16T16:46:49Z

2026-09-16 Dataset for the article "Bidirectional roles of exosomal miR-140-5p on IFN in IAV-infected epithelial cells and macrophages" doi:10.57760/sciencedb.40939 en The dataset comprises all raw data generated for the article "Bidirectional roles of exosomal miR-140-5p on IFN in IAV-infected epithelial cells and macrophages", supporting every figure and supplementary result. Specifically, it includes: (i) exosome characterization data, comprising transmission electron microscopy (TEM) images, nanoparticle tracking analysis (NTA) size profiles, and Western blot (WB) validation of exosomal markers; (ii) raw measurements for IFN-γ and its related signaling pathways, obtained via quantitative real‑time PCR (qPCR) and Western blot; (iii) miRNA profiling data, including qPCR‑based abundance quantification and RNA‑sequencing (RNA‑Seq) raw counts for differential expression analysis; and (iv) clinical study data derived from patient samples. All data are provided in their original formats, primarily as GraphPad Prism files (.pzfx) and Microsoft Excel spreadsheets (.xlsx), to ensure full traceability and reproducibility of the analyses presented in the paper. Influenza A virus (IAV); epithelial cell (EC); macrophage (Mφ); miR-140-5p; exosomes; interferon (IFN). Yan-chun Qin Hui-min Huang Zu-rong Zhang Ying-na Huang Huan-hua Yang Yun-long Song Man-jing Jiang Xu Li Zhong-sheng Jiang Yu Lu Guang-yu Lv Ling Jin Jian-yu Luo WY RESTRICTED dataset Science Data Bank