2026-10-12T08:32:42Z https://www.scidb.cn/oai

10.57760/sciencedb.42501 2026-07-10T15:15:23Z

2026-07-10 LSECs under coupled and decoupled mechanical loadings doi:10.57760/sciencedb.42501 en LSECs exhibit diverse transcriptional landscapes under stretch-shear, stretch, and shear loading modalities in a liver regeneration chip. LSECs were subjected to coupled and decoupled mechanical loadings for 1.5 hours within a liver regeneration chip. RNA was extracted from LSECs immediately after loading for sequencing. RNA libraries were prepared by BGI using standard polyA enrichment and a strand-specific protocol. Raw sequencing data were processed by BGI using the RNAref pipeline. Clean reads were aligned to the mouse reference genome GRCm39 (GCF_000001635.27). Gene expression quantification was performed, and raw read counts as well as TPM (transcripts per million) values were generated for each sample.This dataset includes: (1) raw RNA-seq FASTQ files for 13 samples, and (2) a processed gene expression matrix containing raw counts and TPM values. LSEC; coupled; decoupled; mechanical Shu Xinyu Du Yu Long Mian Chen Guangyao Song Chaoyang Zhang Yan Lv Shouqin EMBARGO https://creativecommons.org/licenses/by/4.0/ dataset http://www.doi.org/10.64898/2026.07.13.738320 Science Data Bank