2026-10-10T18:24:18Z https://www.scidb.cn/oai

10.57760/sciencedb.46311 2026-08-17T10:51:31Z

2026-08-17 RNA sequencing and chromatin immunoprecipitation sequencing datasets of the transcription factor SP6 in human trophoblast cells doi:10.57760/sciencedb.46311 en This dataset contains 22 bulk RNA-seq transcriptome samples and 20 in situ ChIP-seq samples from human cytotrophoblast-like cells derived from expanded potential stem cells (EPSCs). It profiles genome-wide gene expression, the occupancy of transcription factor SP6, and three histone modifications (H3K27ac, H3K4me3, H3K27me3) in control and SP6-knockout cell lines with biological replicates. This multi-omics resource supports investigations into the transcriptional and epigenetic mechanisms of human trophoblast development and placental stem cell fate determination. Human; Trophoblast cells; SP6; ChIP-seq; RNA-seq Xueying Zhu Fengying Zhang Chaorong Yue Xue Wang Jia Shi Rui Wang Xiaoming Yao Peng Wei Xuefei Gao* Yanglin Chen* PUBLIC https://creativecommons.org/licenses/by/4.0/ dataset Science Data Bank