2026-10-13T16:14:33Z https://www.scidb.cn/oai

10.57760/sciencedb.j00139.00167 2025-02-18T09:23:58Z

2025-02-18 Single-Cell Sequencing Analysis of YTHDF1 knockout Retina doi:10.57760/sciencedb.j00139.00167 en To profile the transcriptomic alteration in each cell types and investigate the structural changes of neural retinas during pathological degeneration, we performed single-cell RNA-sequencing (scRNA-seq) of the retinal cells from Ythdf1+/+ and Ythdf1-/- mice at 8 months of age (n = 3 retinas from 3 mice per group). The neural retinas were isolated and dissociated into single-cell suspensions, which were then subjected to scRNA sequencing using the BD Rhapsody scRNA-seq platform. Epitranscriptomics; N6-methyladenosine (m6A); Inherited retinal dystrophies (IRDs); YTHDF1; Single-cell RNA sequencing Yeming Yang Xianjun Zhu PUBLIC https://creativecommons.org/publicdomain/zero/1.0/ dataset Science Data Bank