2026-10-12T23:51:12Z https://www.scidb.cn/oai

10.57760/sciencedb.j00139.00242 2026-03-11T10:19:32Z

2026-03-11 RNA-seq of colon tissue from DSS-colitis mice treated with SPX peptides doi:10.57760/sciencedb.j00139.00242 en This study used RNA-seq to investigate the therapeutic mechanisms of SPX peptides in colitis. Colon tissues were collected from five groups of male mice: control, DSS-induced colitis, and DSS-induced colitis treated with SPX1, ggSPX2, or ggGAL peptides. Comparative transcriptomic analysis aims to identify gene expression changes and molecular pathways underlying the superior therapeutic efficacy of SPX peptides over GAL in inflammatory bowel disease. RNA-seq; SPX; DSS; colitis Jing-Wen Xue Ting Zhang Xiang-Lin Kong Kun Zheng Yu-Wei Chen Kai-Li Ma Tao Zeng Juergen Brosius Fei Xu Shan-Shan Lai Cheng Deng EMBARGO https://creativecommons.org/licenses/by-sa/4.0/ dataset http://www.doi.org/10.24272/j.issn.2095-8137.2025.489 Science Data Bank