2026-10-13T09:47:43Z https://www.scidb.cn/oai

10.57760/sciencedb.j00186.00470 2024-03-17T16:43:04Z

2024-03-17 Feasibility of medical radioisotope production based on the proton beams at China Spallation Neutron Source doi:10.57760/sciencedb.j00186.00470 en The data related to the article "Feasibility of medical radioisotope production based on the proton beams at China Spallation Neutron Source" submitted to the journal of Nuclear Science and Techniques. The utilization of a proton beam from the China Spallation Neutron Source (CSNS) for producing medical radioisotopes is appealing owing to its high current intensity and high energy. The medical isotope production based on the proton beam at the CSNS significant for the development of future radiopharmaceuticals, particularly for the α-emitting radiopharmaceuticals. The production yield and activity of typical medical isotopes were estimated using a FLUKA simulation. The results indicate that the 300-MeV proton beam with a power of 100 kW at CSNS-II is highly suitable for proof-of-principle studies of most medical radioisotopes. In particular, this proton beam offers tremendous advantages for the large-scale production of alpha radioisotopes, such as 225Ac, whose theoretical production yield can reach approximately 57 Ci/week. Based on these results, we provide perspectives on the use of CSNS proton beams to produce radioisotopes for medical applications. The data files consists of 3 separate Excel files, which are obtained from the simulation results. The details are described as follows:Intarget_yield.xlsx: In-target production yield of radioisotopes at CSNS-II.alpha_yield_time.xlsx: Evolution of the activity of alpha-emitting radioisotopes with irradiation time.lanthanide_yield_time.xlsx: Evolution of the activity of neutron-deficient lanthanide isotopes with irradiation time. See the article for more details. CSNS proton beam; Medical isotope production; α-emitting radionuclides; nuclidic purity analysis Bing Jiang (姜炳) Binbin Tian （田斌斌） Hantao Jing (敬罕涛) Qifan Dong (董启凡) PUBLIC https://creativecommons.org/licenses/by/4.0/ dataset http://www.doi.org/10.1007/s41365-024-01438-w Science Data Bank