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    <identifier>10.57760/sciencedb.j00217.04813</identifier>
    <datestamp>2024-12-13T21:05:07Z</datestamp>
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  <dc:date>2024-12-13</dc:date>
  <dc:title>Application of exosome-mediated tumor-macrophage communication in breast cancer</dc:title>
  <dc:identifier>doi:10.57760/sciencedb.j00217.04813</dc:identifier>
  <dc:language>en</dc:language>
  <dc:description>在全球女性中，BC 是一种普遍且致命的癌症。TAMs 是 BC TME 中的关键细胞，在 BC 的发生和治疗中发挥着不可或缺的作用。外泌体是广泛存在于体液中的 EV，携带多种生物活性分子，如蛋白质、脂质和核酸。作为细胞间物质交换的桥梁，外泌体是肿瘤细胞与 TAM 之间通讯的重要介质。本文总结了 BC 和 TAMs 之间外泌体介导的通讯的新进展。重点是外泌体的作用和机制。同时，我们讨论了在 BC 和 TAMs 之间靶向外泌体的可能治疗方案，为治疗 BC 提供新思路。</dc:description>
  <dc:subject>exosome; cancer; treatment</dc:subject>
  <dc:creator>Rongquan.Gong</dc:creator>
  <dc:creator>Xiao.Huang</dc:creator>
  <dc:creator>An.Xu</dc:creator>
  <dc:creator>Deyuan.Fu</dc:creator>
  <dc:rights>PUBLIC</dc:rights>
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