2026-10-15T04:21:52Z https://www.scidb.cn/oai

10.57760/sciencedb.nprd.00038 2026-09-07T10:47:58Z

2026-09-07 Based on Network Pharmacology and Experimental Verification to Explore the Mechanism of Guizhi‑Jialong‑Muli Decoction in the Treatment of Insomnia doi:10.57760/sciencedb.nprd.00038 en This research data covers multi-dimensional indicators such as neuroinflammatory markers (IBA, GFAP), neurotransmitters (5-HT, GLU), inflammatory factors (TNF - α, IL-6, IL-1 β), protein expression (AKT, P-AKT, PI3K, P-PI3K), and open field behavioral tests. All tables are set with six unified experimental groups: Control (blank control group), Model (disease model group), Estazolam (positive control group of estazolam), GZJLMT-L/M/H (Guizhi Jialonggu Oyster soup GZJLMT low, medium, and high dose groups). In terms of the number of records, the IBA, GFAP, and 5-HT tables each contain 6 repeated experimental data; The TNF - α, IL-6, IL-1 β, and GLU tables each contain 12 items (6 for serum and 6 for tissue samples); The open field data table contains 24 items, divided into two groups of "central dwell time" and "central dwell frequency" (12 items each), with behavioral labels ranging from experimental numbers Exp_1 to Exp_12. All experiments were conducted with 6 or 12 biological replicates to ensure data reliability. Some table column names have slight formatting differences (such as hyphens and underscores), but the group meanings are consistent.  Guizhi Jia Longgu Muli Decoction; Insomnia; Network pharmacology; Molecular docking; Molecular dynamics simulation; Experimental verification yi shun EMBARGO https://creativecommons.org/licenses/by-nc-nd/4.0/ dataset Science Data Bank