2026-10-14T23:41:30Z https://www.scidb.cn/oai

10.57760/sciencedb.nprd.00052 2026-01-19T10:08:31Z

2026-01-19 Inhibitory effect and mechanism of diaporisoindole B on phenotypic transformation and inflammatory response of vascular smooth muscle cells doi:10.57760/sciencedb.nprd.00052 en An inflammatory cell model was established by adding lipopolysaccharides (LPS) to rat aortic VSMCs. Cell viability was detected by CCK-8 assay, intracellular reactive oxygen species levels were detected by DCFH-DA dye assay, the effects of DPB on VSMC proliferation and migration were determined by scratch assay and Transwell assay, mRNA levels of relevant inflammatory factors were detected by RT qPCR, and protein levels of relevant pathways were detected by Western blot.  vascular smooth muscle cells; inflammation; phenotypic transformation; NF-κB; MAPK Liu Hongju PUBLIC https://creativecommons.org/licenses/by-nc-nd/4.0/ dataset Science Data Bank