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    <responseDate>2026-10-12T18:33:22Z</responseDate>
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    <identifier>10.57760/sciencedb.psych.01126</identifier>
    <datestamp>2026-08-09T10:00:19Z</datestamp>
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  <dc:date>2026-08-09</dc:date>
  <dc:title>Code and data for: Shared epigenetic architecture links chronic pain and anxiety</dc:title>
  <dc:identifier>doi:10.57760/sciencedb.psych.01126</dc:identifier>
  <dc:language>en</dc:language>
  <dc:description>Zhang et al. identified a shared epigenetic architecture linking chronic pain and trait anxiety across independent chronic and acute TMD cohorts. Here, we provide data and code to support the review and meta-analysis. The study included two cohorts from the Orofacial Pain: Prospective Evaluation and Risk Assessment (OPPERA) study: OPPERA I comprised 932 participants from a case&amp;ndash;control study of chronic painful temporomandibular disorder (TMD), while OPPERA II included 77 participants from a longitudinal study of recent-onset painful TMD.</dc:description>
  <dc:subject>temporomandibular disorder; trait anxiety; DNA methylation; shared epigenetic architecture; molecular signature; disease stratification</dc:subject>
  <dc:creator>Ming Zhang</dc:creator>
  <dc:creator>Xiang Ao</dc:creator>
  <dc:creator>Luda Diatchenko</dc:creator>
  <dc:rights>EMBARGO</dc:rights>
  <dc:rights>https://creativecommons.org/licenses/by-nc/4.0/</dc:rights>
  <dc:type>dataset</dc:type>
  <dc:publisher>Science Data Bank</dc:publisher>
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